Works fine with my creators version of W10.
Havew you changed the way to install MP3tag (from local to portable or vice versa)?
If so: do you have sufficient access rights for the installation folder and all the other possible locations (see here for options: /t/964/1 )
Have you tried to rename the file mp3tag.cfg and start MP3tag with a fresh configuration?
This is what I would check right now.